Cell Lines and Cell Cultures
ATCC Aeromonas hydrophila; Strain CDC 359-60; genomic DNA
Genomic DNA isolated from Aeromonas hydrophila strain CDC 359-60 (ATCC 7966). This whole-genome sequenced product can be used in PCR and other molecular biology applications.
ATCC Acinetobacter radioresistens
Acinetobacter radioresistens strain IAM 13186 [DSM 6976, FO-1] is a bacterial type strain that was isolated in 1978 from a cotton tampon. The depositor states that this strain is radiation resistant.
Genscript Corporation CHO-K1/CMKLR1/G15 Stable Cell
The orphan receptor ChemR23 (also referred to as CMKLR1 or DEZ) is a G-protein coupled receptor (GPCR) with homology to neuropeptide and chemoattractant receptors ChemR23 is also a G i-linked receptor expressed primarily by monocytes M s and plasmacytoid dendritic cells CMKLR1 has been shown to be expressed by DC generated in vitro from monocytes to mediate their migration to the proteolytically regulated chemoattractant chemerin and CMKLR1 may be a key mediator of pDC recruitment from the blood into tissue sites enriched in active chemerin
ATCC Human adenovirus 1; Strain: Type 1
Human adenovirus 1 strain Type 1 is an animal virus propagated in HeLa cells (ATCC CCL-2). This strain was isolated from cat feces in Budapest, Hungary, in 1997.
Invivogen HEK-Blue™ IFN-λ Cells, Detects Bioactive IFN-λs, Monitors JAK/ISGF3 Pathway, 1 vial
The HEK-Blue™ IFN-λ Cells from InvivoGen are engineered human embryonic kidney (HEK293) cells designed for detecting bioactive human type III interferons (IFN-λs). These cells effectively monitor the JAK/ISGF3 pathway, providing a valuable tool for understanding IFN-λ signaling and screening potential inhibitors. This product stands out due to its specificity for human and murine IFN-λs, facilitating advanced research in therapeutic applications.
Eurofins Discoverx ChemiBrite FSH Glycoprotein Hormone Receptor Stable Cell Line, 2 vials. (HTS178L)
The ChemiBrite FSH Glycoprotein Hormone Receptor cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. follicle stimulating hormone) based activation of FSHR GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses FSHR alongside exogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. ChemiBrite cells also express a clytin variant, allowing for luminescent as well as fluorescent signal detection. Upon activation of FSHR, the resulting calcium activity can be assayed in either detection mode. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Lonza Walkersville HPAEC – Human Pulmonary Artery Endothelial Cells
Lonza's Human Pulmonary Artery Endothelial Cells (HPAEC) and media are convenient and easy to use, allowing the researcher to focus on results. Cryopreserved HPAEC cells are shipped in third passage. Proliferating cells are shipped in fourth passage. Cells isolated from Diabetes Type 1 and 2 are also available.Clonetics cells, medium and reagents are quality tested together and guaranteed to give optimum performance as a complete cell system.Benefits:Assured for experimental use up to 15 population doublings All cells test negative for mycoplasma, bacteria, yeast, and fungiHIV-1, Hepatitis B and Hepatitis C are not detected for all donors and/or cell lotsCharacterized by morphological observation throughout serial passageCertificate of Analysis provided for every cell lot Applications:Hypertension Arteriosclerosis InflammationOncologyDrug screening Content:1 x Cryopreserved ampule of HPAEC containing ≥ 500,000 cells
ATCC Pseudomonas putida; KT2440; genomic DNA
Genomic DNA isolated from Pseudomonas putida strain KT2440. This bacterial strain is also available as ATCC Catalog No.: 47054™.
ATCC Aeromonas hydrophila; 6 x 0.3mL
ATCC 35654-MINI-PACK™ consists of 6 ready-to-use vials of ATCC 35654™ frozen in 200 μL of glycerol stock, eliminating the need to rehydrate and culture the strain prior to use. Each vial is provided with a 2-D barcode for easy storage and tracking, as well as peel-off labels for fast and reliable recordkeeping.
Eurofins Discoverx ChemiScreen BB2 Bombesin Receptor Stable Cell Line, 2 vials. (HTS084C)
The ChemiScreen BB2 Bombesin Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. bombesin) based activation of GRPR GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses GRPR alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of GRPR, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
ATCC STO; Embryonic Fibroblast; Mouse (Mus musculus)
STO is a fibroblast cell line that was isolated from the embryo of a mouse. This cell line was deposited by G Martin.
ATCC MOVAS; Aortic Smooth Muscle; Mouse (Mus musculus)
MOVAS is a spindle-shaped cell line that was isolated in 1999 from the smooth muscle of an adult mouse. This cell line was deposited by M Husain and can be used in cardiovascular disease research.
Eurofins Discoverx InCELL Hunter A549 SIK1 Kinase Binding Cell Line, 2 vials. (96-0051C15)
The InCELL Hunter A549 SIK1 Kinase Binding Cell Line is a stable, engineered cell line for use in studying small molecule drug candidates that engage with kinases. This cell line enables assessment of compound-engagement-based stabilization of SIK1 via detection of SIK1 levels. This product uses EFC technology. The cell line included overexpresses SIK1 target protein fused to ProLabel. In the absence of compound that binds and stabilizes the target, this protein is denatured by the heat treatment and no EFC signal is produced. When compound engages and heat-stabilizes the target, EA contained in the detection reagent produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/kinases.
ATCC SU-DHL-6; Large Cell Lymphoma; Human (Homo sapiens)
SU-DHL-6 is a lymphoblast-like cell that was isolated from the peritoneal effusion of a White, 43-year-old, male patient with large cell lymphoma. This cell line was deposited by A Epstein in 1977.